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  • The Xpert MTB/RIF is a cartridge-based, automated diagnostic test that can identify Mycobacterium tuberculosis (MTB) and resistance to rifampicin (RIF). It was co-developed by Cepheid, Inc. and Foundation for Innovative New Diagnostics, with additional financial support from the US National Institutes of Health (NIH) and technical support from the University of Medicine and Dentistry of New Jersey (UMDNJ). In December 2010, WHO endorsed the automated NAAT for use in TB endemic countries and declared it a major milestone for global TB diagnosis. This follows 18 months of rigorous assessment of its field effectiveness in TB, MDR-TB and TB/HIV co-infection. This test, and others that are likely to follow, have the potential to revolutionize the diagnosis of TB. Tuberculosis is one of the deadliest public health threats today, but there remains a lack of effective diagnostic tools. According to the WHO, only 5 percent of the estimated global burden of multi-drug-resistant tuberculosis ...
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